Osteoporosis is a condition of atrophy of the bones characterized by a reduction in the mass of bones per unit volume. Osteoporosis is the most common metabolic bone disease that occurs with advancing age. Normal bone structure is maintained by the continuous bone breakdown (by osteoclasts) and new bone formation (by osteoblasts) with advancing age there is more bone resorption than formation, collapse, and fracture, especially of vertebrae are common, causing pain and decrease in height Causes/etiology: Osteoporosis may occur due to a combination of low calcium intake and hormonal physical and circulatory factors. Bed rest and immobilization increase calcium resorption from the weight-bearing bones and urinary and stool calcium excretion. Aged immobilized patients rapidly develop osteoporosis while exercise and physical therapy prevent its progress. Deficiency of estrogen, removal of ovaries, smoking, alcohol, excess phosphorus intake, and sedentary habits produce osteoporosis. Lacto...
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