Definition
Vitamin B12 is an essential water-soluble vitamin. There are several forms of vitamin B12 that contain the mineral cobalt. Another name for vitamin B12 is cobalamins. Two types active in humans are methylcobalamin and 5-deoxyadenosylcobalamin. Vitamin B12 is bound to protein in animal foods. Vitamin B12 is released in the stomach by gastric protease and hydrochloric acid. Synthetic vitamin B12 in dietary supplements is in its free form and does not require separation. Free vitamin B12 combines with intrinsic factors in the stomach and absorbed from the small intestine into the bloodstream. About 55% of a 1 microgram oral dose is absorbed. Absorption depends on the availability of intrinsic factors. The amount of vitamin B12 absorption also depends on other factors like the use of protein pump inhibitors for acid reflux and heartburn.
Reasons why vitamin B12 is an essential vitamin
Essential vitamins are vitamins your body can't make that must come from your diet. Vitamins that are water-soluble are not stored in your body. So, your diet must provide enough Vitamin B12 daily. Vitamin B12 is required for -
- DNA synthesis
- red blood cell formation
- converting homocysteine to methionine
- neurological functions
Vitamin B12 US-RDA
The current USA Recommended Dietary Allowance (RDA) or Daily Value for vitamin B12 according to the National Institutes of Health varies with age.
*** Pregnant woman 2.6 mcg, Lactating woman 2.8 mcg
A microgram is 1/1,000,000 gram. It takes 1000 micrograms to equal 1 milligram. The daily requirement for vitamin B12 is very small. The USRDA has a safety factor to prevent the vitamin B12 deficiency. Pernicious anemia is an autoimmune disease that destroys stomach cells producing intrinsic factors. To be absorbed vitamin B12 must bind to intrinsic factors in your stomach. Vitamin B12 deficiency occurs when there is little or no intrinsic factor. A deficiency can cause megaloblastic anemia and neurological disorders. Without intrinsic factors, no amount of dietary or supplemental vitamin B12 will prevent or cure vitamin B12 deficiency.
Symptoms of vitamin B12 deficiency
Symptoms of vitamin B12 deficiency include -
- dementia
- weakness
- megaloblastic anemia
- constipation
- depression
- loss of appetite
- numbness
- mouth or tongue soreness
- weight loss
- confusion
- fatigue
- tingling in hands and feet
Richest sources of vitamin B12
- seafood
- eggs
- fish
- meat
- milk
- poultry
- fortified foods and
- milk products
Here are 20 common high vitamin B12 foods
- At number one is cooked beef liver, a 3-ounce serving provides 70 micrograms or almost 3000% of the RDA.
- 3 ounces of cooked clams provide 450% of the RDA at 10.7 micrograms.
- 3 ounces of canned sardines provides over 300% of the RDA at 7.6 micrograms.
- the same for three ounces of cooked wild-caught sockeye salmon.
- a 3 ounce serving of cooked trout provides 160% of the RDA at 3.8 micrograms.
- 3 ounces of cooked 80/20 ground beef has about 2.3 micrograms.
- 3 ounces of cooked lamb provides slightly more at 2.23 micrograms.
- 3 ounces of canned light tuna provides about 90%of the RDA at 2.2 micrograms.
- 3 ounces of cooked Cod provides 80% of the RDA at 1.9 micrograms.
- 3 ounces of cooked beef tenderloin has about 1.5 micrograms.
- 3 ounces of cooked squid provides 1.3 micrograms.
- One cup of low-fat milk provides 50% of the RDA at 1.2micrograms.
- 6 ounces of plain yogurt has about one microgram.
- One ounce of Swiss and other cheeses provides about 35% of the RDA at 0.85 micrograms.
- 3 ounces of cooked shrimp has about 0.8 micrograms.
- cooked chicken breast - a 3-ounce serving provides 0.23 micrograms, about 10 percent of the recommended dietary allowance.
- Chicken eggs - one large egg has 0.35 micrograms.
- 3 ounces of cooked turkey breast provides 30 percent of the RDA at 0.7 micrograms
- 3 ounces of lean cooked ham provides about half a microgram.
- Fortified cereals with 0.6 micrograms per serving provide about 25% of the RDA.
Very useful information
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